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Group B streptococcus infections may be serious for the neonates. The infection can occur during the birth, by contact with the genital area. That is why the detection of this bacteria is systematically realised in pregnant women between 34 and 37 weeks of amenorrhea in order to give prophylactic antibiotic treatment in case or positive carriage. This strategy presents 2 disadvantages : (1) detection of the group B streptococcus at 34 and 37 weeks of amenorrhea in not predictive of a carriage at delivery, (2) many pregnant women escape from systematic screening, leading to a systematic antibiotic treatment, which means useless costs, and useless antibiotic exposure with resistant bacteria selection. Real time polymerase chain reaction (PCR) allows a rapid detection anytime with no specific microbiological qualification. The aim of the study is to assess the economic outcomes of this strategy and the epidemiological values for St Etienne hospital.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Real time PCR monitoring | Women giving birth at the St Etienne Teaching Hospital |
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| Measure | Description | Time Frame |
|---|---|---|
| number of women receiving a useless antibiotic prevention | 1 day |
| Measure | Description | Time Frame |
|---|---|---|
| economic outcomes | 1 day | |
| epidemiological outcomes for group B streptococcus | 1 day | |
| diagnosis efficacy of the real time PCR |
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Inclusion Criteria:
Exclusion Criteria:
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All pregnant women having a pregnancy follow up with Streptococcus agalactiae monitoring according with french recommandations.
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| Name | Affiliation | Role |
|---|---|---|
| Bruno POZZETTO, MD PhD | CHU de Saint-Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Saint-Etienne | Saint-Etienne | 42055 | France |
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Vaginal swab
| 1 day |