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This study is designed to study the pathways through which short sleep duration or poor sleep quality can lead to an increased risk of developing diabetes and obesity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Baseline | Experimental | Subjects are tested under normal sleep conditions for carbohydrate metabolism and appetite regulation. |
|
| Sleep restriction | Experimental | Subjects are tested under sleep restriction for carbohydrate metabolism and appetite regulation. |
|
| Reduced sleep quality | Experimental | Subjects are tested under a poor sleep quality condition for carbohydrate metabolism and appetite regulation. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Baseline | Other | Subjects are allowed time in bed for sleep as their usual time at home. |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Disposition Index reflecting Diabetes Risk as a result of decreased sleep duration and/or quality. | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Esra Tasali, MD | University of Chicago | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Chicago | Chicago | Illinois | 60637 | United States |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| C074807 | BaseLine dental cement |
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| Sleep restriction |
| Other |
Subjects sleep is reduced to 4.5 hours in bed for 4 nights. |
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| Reduced Sleep Quality | Other | Subjects sleep quality is reduced for 4 nights. |
|
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D004700 | Endocrine System Diseases |