Pharmacokinetic and Exploratory Biomarker Study of ABT-126 in Healthy Volunteers

A Pharmacokinetic and Exploratory Biomarker Study of ABT-126 in the Cerebrospinal Fluid (CSF) of Healthy Subjects

The objectives of this study are to determine the cerebrospinal fluid (CSF) levels of ABT-126 and to examine the effects of ABT-126 on exploratory biomarkers after administration of a single does of ABT-126 in healthy volunteers.

Inclusion Criteria:

• Healthy male or female subjects between 18 and 50 years of age

Exclusion Criteria:

• History of bleeding disorders or Deep Vein Thrombosis
• History of spinal surgery
• History of migraine headaches, or other types of headaches occuring more than 2 times per month, or history of spinal disc disease, or chronic, significant low back pain