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Slow enrollment
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Regadenoson is approved in the US under the brand name Lexiscan for myocardial perfusion imaging. This study will test whether regadenoson is an appropriate stress agent for stress echocardiography.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Regadenoson alone | Experimental |
| |
| Regadenoson with exercise | Experimental |
| |
| Regadenoson with contrast agent | Experimental |
| |
| Regadenoson with contrast agent (perfusion) | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| regadenoson | Drug | 400 ug, IV |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cardiac wall motion and perfusion abnormalities at rest and with regadenoson stress, with regadenoson stress and low level exercise, and with regadenoson stress and an echocontrast agent. | Within 12 minutes after dosing |
| Measure | Description | Time Frame |
|---|---|---|
| Various safety data will be collected, including adverse events, heart and blood pressure levels, ECG data, clinical laboratory results, and concomitant medications. | Up to day 29 after dosing |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Roxy Senior | Northwick Park Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Northwick Park Hospital | Harrow | HA1 3UJ | United Kingdom |
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| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D001161 | Arteriosclerosis |
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| ID | Term |
|---|---|
| C430916 | regadenoson |
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| D001157 |
| Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |