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The purpose of this study is to correlate changes of visual function three weeks after photocoagulation for macular edema, with changes of center point thickness and macular volume.
Photocoagulation for clinically significant macular edema is effective to reduce the incidence of moderate visual loss. Selective photocoagulation for focal macular edema statistically reduces macular thickening, measured with optical coherence tomography, as early as two weeks after treatment, without significant changes over center point thickness. Although anatomic improvement has been demonstrated with OCT, clinical improvement takes longer to be evident: the Early Treatment Diabetic Retinopathy Study describe that clinical differences in visual function are after the eight month, and all the treatment strategies for macular edema used in this study were associated with an increased rate of moderate visual loss, during the first six weeks. Differences in research can achieve statistical significance, without clinical significance. A study was conducted to identify changes of visual function three weeks after photocoagulation for focal macular edema, and to correlate them with changes of CPT and macular volume, in order to compare the behavior of anatomical changes with visual changes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| diabetic macular edema | type 2 patients who had been treated with selective photocoagulation for clinically significant macular edema |
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| Measure | Description | Time Frame |
|---|---|---|
| visual capacity (under subjective refractive correction was measured in decimal equivalent) | before the treatment and 3 weeks after photocoagulation | |
| center point thickness (measured in µm) | before the treatment and 3 weeks after photocoagulation | |
| macular volume (measured in mm3) | before the treatment and 3 weeks after photocoagulation |
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Inclusion Criteria:
Exclusion Criteria:
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Target population were type 2 diabetics from Mexico City and its metropolitan area, accessible population were the patients who attended a General Hospital in Mexico City
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| Name | Affiliation | Role |
|---|---|---|
| Dulce M Razo Blanco Hernandez, MD | Hospital Juarez de Mexico | Study Director |
| Virgilio Lima Gomez, MD, MSc | Hospital Juarez de Mexico | Study Chair |
| Aleyda S Cruz Diaz, MD | Hospital Juarez de Mexico | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Juarez de Mexico | Mexico City | Mexico City | 07760 | Mexico |
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| ID | Term |
|---|---|
| D003930 | Diabetic Retinopathy |
| D008269 | Macular Edema |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
| D003925 | Diabetic Angiopathies |
| D014652 | Vascular Diseases |
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| D002318 |
| Cardiovascular Diseases |
| D048909 | Diabetes Complications |
| D003920 | Diabetes Mellitus |
| D004700 | Endocrine System Diseases |
| D008268 | Macular Degeneration |
| D012162 | Retinal Degeneration |