The Effects of Isoflavone and Estrogen in Sex Response in Climacteric Women

Effects of Isoflavone and Estrogen in Sex Response in Climacteric Women

Climacterium is marked by hypoestrogenism and it is associated to drastic vasomotors symptoms, genital atrophy and humor alteration. Additionally, these symptoms impair sexual life and life quality. These effects can be counteracted by administration of estrogen therapy. However, estrogen therapy has side effects and isoflavone has been proposed as an estrogen substitute in reposition therapy. The aim of the randomized controlled trial is to evaluate the effects of isoflavone in the sex life assessed by a modified McCoy's sexual questionnaire.

Inclusion Criteria:

• women aged 45-65 years old
• presenting climacteric symptoms
• sexual complaints

Exclusion Criteria:

• hormonal therapy
• counter indication to hormonal therapy
• uncontrolled comorbidities