Indomethacin Eyedrops Compared With Ketorolac Eyedrops for Ocular Inflammation Following Cataract Surgery

This study is being conducted to show that indomethacin is at least as effective as ketorolac for the prevention of ocular inflammation following cataract surgery.

Inclusion Criteria:

• Subjects must be planning to undergo cataract surgery on one eye by phacoemulsification with posterior chamber intraocular lens, using topical or general anaesthesia.
• Subjects must have a preoperative flare ≤ 15 ph/ms, measured with a laser flare meter(LFM) without pharmacological pupil dilation, within the 2 months preoperatively.

Exclusion Criteria:

• Subjects who have any progressive pathology requiring the use of topical or systemic anti-inflammatory or anti-infectious agents.
• Subjects who take acetylsalicylic acid at doses > 100 mg daily and cannot discontinue usage during the study.
• Subjects who have a history of asthma linked to acetylsalicylic acid or other nonsteroidal anti-inflammatory (NSAI) drug administration.
• Subjects with immunodepression.
• Subjects with a history of intolerance to the study drug or to any NSAI drug.
• Subjects who are monocular for any reason other than cataract.
• Subjects who are treated with local or systemic anti-inflammatory drugs within 10 days prior to inclusion.