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| Name | Class |
|---|---|
| Astellas Pharma Canada, Inc. | INDUSTRY |
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This is a multicentre, observational, non-interventional, retrospective analysis by chart review.
This study will compare differences in patient and graft related outcomes in renal transplant recipients followed in regional transplant centers versus satellite clinics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1. Community Based Clinics | Patient charts from community based nephrology clinics |
| |
| 2. Regional Clinics | Patient charts from regional transplant clinics |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Chart Review | Other | Chart review of patients / graft outcome in renal transplant recipients |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in renal function over 6-18 months estimated by change in serum creatinine and glomerular filtration rate (GFR) | 6, 12 and 18 months |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of hyperlipidemia, hypertension, weight gain/central adiposity, hypertrichosis, alopecia, diabetes mellitus, bone disease and gingival hyperplasia | 6, 12 and 18 months | |
| Comparison of patients on cyclosporine-vs. tacrolimus-based immunoprophylaxis as well as community-based vs. regional transplant nephrology clinics in both incidence of toxicities and related clinical interventions |
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Inclusion Criteria:
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Canadian subjects post renal transplant, currently being treated with immunosuppressive therapy
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| Name | Affiliation | Role |
|---|---|---|
| Use Central Contact | Astellas Pharma Canada, Inc. | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| New Westminster | British Columbia | V3L3W4 | Canada | |||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20865815 | Background | Keough-Ryan TM, Prasad GV, Hewlett T, Shapiro RJ; Canadian Community Nephrology Study Group. Similar outcomes for Canadian renal transplant recipients followed up in transplant centers and satellite clinics. Transplantation. 2010 Sep 27;90(6):591-6. doi: 10.1097/tp.0b013e3181e9febd. | |
| 20383867 | Background | Prasad GV, Nash MM, Keough-Ryan T, Shapiro RJ. A quality of life comparison in cyclosporine- and tacrolimus-treated renal transplant recipients across Canada. J Nephrol. 2010 May-Jun;23(3):274-81. |
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| 6, 12 and 18 months |
| Vancouver |
| British Columbia |
| V5Z1M9 |
| Canada |
| Moncton | New Brunswick | E1C2Z3 | Canada |
| Saint John | New Brunswick | E2L4L2 | Canada |
| Halifax | Nova Scotia | B3H1V7 | Canada |
| Sydney | Nova Scotia | B1P1P3 | Canada |
| Greater Sudbury | Ontario | P3E5J1 | Canada |
| London | Ontario | N6A5A5 | Canada |
| Mississauga | Ontario | L5M5W9 | Canada |
| Sault Ste. Marie | Ontario | P6A2C4 | Canada |
| Thunder Bay | Ontario | P7E6E7 | Canada |
| Toronto | Ontario | M5C2T2 | Canada |
| Toronto | Ontario | M5G2N2 | Canada |