Caphosol for the Reduction of Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

Caphosol for the Reduction of Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

Patients who have been diagnosed with a head and/or neck cancer commonly develop oral mucositis (OM). The purpose of this study is to estimate the effect of Caphosol on OM and to evaluate if Caphosol had any effect on clinical outcomes which include quality of life, oral intake, swallowing function and pain.

Inclusion Criteria:

• Diagnosed Head and Neck Cancer patients with planned Radiation therapy
• Have at least one of 10 pre-defined anatomic mucosal subsites on view
• Age >/= 18 years
• Life expectancy >/= 6 months
• Planned RT to the head/neck
• Must be able to perform oral rinse

Exclusion Criteria:

• Active infections of oral cavity
• physiologic condition that precludes the use of an oral rinse
• Hypersensitivity to Caphosol ingredients
• Presence of mucosal ulceration at baseline
• Poorly controlled hypertension, DM or other serious medical/psychiatric illness