Low Dose Estriol With Lactobacilli Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women

Low Dose Estriol With Lactobacilli (Gynoflor) Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women: A Randomized, Open, Parallel-Group Study

Recurrent urinary tract infections (UTI) are a problem for postmenopausal women. The aim of this trial is to evaluate the effectiveness of lactobacilli in combination with low dose estriol for preventing recurrent urinary tract infections in postmenopausal women.

Inclusion Criteria:

• Postmenopausal woman
• History of urinary tract infection
• Agree to abstain from self-medication with antibiotics for UTI symptoms
• Agree to abstain from the use of any other intra-vaginal product
• Capable of providing informed consent

Exclusion Criteria:

• Ovarian cancer, cervical cancer, breast cancer
• Estrogen treatment within last 2 years
• Vaginal bleeding
• Antibiotic therapy fewer than three days prior to randomization visit
• Known congenital urologic or gynecologic abnormalities
• Indwelling urinary catheter
• Thromboembolic disease
• Uncompensated liver disease
• Immunosuppressive drug within 60 days