Survival Prediction in HNSCC Based on Gene Expression Profiles From FFPE Tissues
Survival Prediction in HNSCC Based on Gene Expression Profiles From FFPE Tissues
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict survival of patients with head and neck cancer.
PURPOSE: This laboratory study is assessing gene expression profiles in predicting survival of patients with head and neck cancer.
OBJECTIVES:
OUTLINE: Formalin-fixed paraffin-embedded tissue samples are analyzed by DNA microarray analysis for gene expression profiling.
Inclusion Criteria:
Diagnosis of squamous cell carcinoma of the head and neck, including 1 of the following sites:
Stage II-IV disease
Must have received treatment on clinical trial RTOG-9501
Formalin-fixed paraffin-embedded tissue samples available
Exclusion Criteria:
PRIOR CONCURRENT THERAPY: