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| ID | Type | Description | Link |
|---|---|---|---|
| K23HL079073 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Heart, Lung, and Blood Institute (NHLBI) | NIH |
| American Society of Hematology | OTHER |
| Medical College of Wisconsin | OTHER |
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The overall goal of this project is to determine the feasibility of conducting a cognitive intervention for children with sickle cell disease.
The primary aims of this clinical trial are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| General Tutoring Group | Active Comparator | Participants will receive general tutoring in the subject of his/her choice. |
|
| Tutoring + Memory Training Group | Experimental | Participants will receive tutoring and memory training. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| General Tutoring | Behavioral | Participants will be tutored for approximately 8-10 hours per month during the school year. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Full Scale IQ (FSIQ) (WASI) | The WASI is a brief, reliable measure of intelligence. Participants engage in 4 subtests: Block Design, Vocabulary, Similarities, and Matrix Reasoning. Participants receive a raw score on each of these 4 subtests. This raw score is converted to a T score using a score chart in the WASI manual. The T scores from all 4 subtests are summed together to obtain a Full Scale Sum of T Scores. This Full Scale Sum of T Scores is converted to a Full Scale IQ-4 Composite Score using a score chart published in the WASI manual. Higher scores indicate better intelligence. FSIQ-4 Range: 40-160. Average FSIQ-4 =100, standard deviation is +/- 15. | After >/= 50 hours of tutoring |
| Verbal IQ (PIQ) (WASI) | The VIQ score is comprised from the Vocabulary and Similarities subtests of the WASI-4. The raw scores from these subtests are converted to T scores using score charts in the manual. The T scores are summed together for a Verbal Sum of T Scores. This score is converted to a Composite VIQ score using a score chart in the manual. Higher scores = better Verbal IQ. Range = 45-160. Average = 100; standard deviation +/- 15. | After >/= 50 hours of tutoring |
| Performance IQ (PIQ) (WASI) | The PIQ score is comprised from the Matrix Reasoning and Block Design subtests of the WASI-4. The raw scores from these subtests are converted to T scores using score charts in the manual. The T scores are summed together for a Performance Sum of T Scores. This score is converted to a Composite PIQ score using a score chart in the manual. Higher scores = better Performance IQ. Range = 45-160. Average = 100; standard deviation +/- 15. | After >/= 50 hours of tutoring |
| Letter Word Identification T Score (WJ-III) | This sub-test measures a student's word identification skills. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Allison King, MD, MPH | Washington University School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Washington University School of Medicine/St. Louis Children's Hospital | St Louis | Missouri | 63110 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 12794531 | Background | Yerys BE, White DA, Salorio CF, McKinstry R, Moinuddin A, DeBaun M. Memory strategy training in children with cerebral infarcts related to sickle cell disease. J Pediatr Hematol Oncol. 2003 Jun;25(6):495-8. doi: 10.1097/00043426-200306000-00014. | |
| 17548550 | Result | King AA, White DA, McKinstry RC, Noetzel M, Debaun MR. A pilot randomized education rehabilitation trial is feasible in sickle cell and strokes. Neurology. 2007 Jun 5;68(23):2008-11. doi: 10.1212/01.wnl.0000264421.24415.16. |
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21 patients completed informed consent to participate in the study. 3 withdrew before the start of the study so they were never assigned to study arms.
All participants are patients of the Pediatric Division of Hematology at Washington University School of Medicine and St. Louis University School of Medicine. Participants will be recruited during regularly scheduled clinic visits.
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| ID | Title | Description |
|---|---|---|
| FG000 | General Tutoring Group | Participants will receive general tutoring in the subject of his/her choice. General Tutoring: Participants will be tutored for approximately 8-10 hours per month during the school year. |
| FG001 | Tutoring + Memory Training Group | Participants will receive tutoring and memory training. General Tutoring: Participants will be tutored for approximately 8-10 hours per month during the school year. Memory Training: Participants will receive memory training for approximately 8-10 hours per month during the school year. Specific memory training strategies used will include silent rehearsal training and semantic clustering training. |
| Title | Milestones | Reasons Not Completed | ||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
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| ID | Title | Description |
|---|---|---|
| BG000 | General Tutoring Group | Participants will receive general tutoring in the subject of his/her choice. General Tutoring: Participants will be tutored for approximately 8-10 hours per month during the school year. |
| BG001 | Tutoring + Memory Training Group |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Categorical | Count of Participants |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Full Scale IQ (FSIQ) (WASI) | The WASI is a brief, reliable measure of intelligence. Participants engage in 4 subtests: Block Design, Vocabulary, Similarities, and Matrix Reasoning. Participants receive a raw score on each of these 4 subtests. This raw score is converted to a T score using a score chart in the WASI manual. The T scores from all 4 subtests are summed together to obtain a Full Scale Sum of T Scores. This Full Scale Sum of T Scores is converted to a Full Scale IQ-4 Composite Score using a score chart published in the WASI manual. Higher scores indicate better intelligence. FSIQ-4 Range: 40-160. Average FSIQ-4 =100, standard deviation is +/- 15. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | General Tutoring Group | Participants will receive general tutoring in the subject of his/her choice. General Tutoring: Participants will be tutored for approximately 8-10 hours per month during the school year. |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Dr. Allison King | Washington University | 314-454-4291 | king_a@wustl.edu |
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| ID | Term |
|---|---|
| D000755 | Anemia, Sickle Cell |
| ID | Term |
|---|---|
| D000745 | Anemia, Hemolytic, Congenital |
| D000743 | Anemia, Hemolytic |
| D000740 | Anemia |
| D006402 | Hematologic Diseases |
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| ID | Term |
|---|---|
| D000091942 | Cognitive Training |
| ID | Term |
|---|---|
| D000066530 | Neurological Rehabilitation |
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
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| Memory Training | Behavioral | Participants will receive memory training for approximately 8-10 hours per month during the school year. |
|
| After >/= 50 hours of tutoring |
| Reading Fluency T Score (WJ-III) | This sub-test measures a student's ability to read simple sentences quickly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | After >/= 50 hours of tutoring |
| Calculations T Score (WJ-III) | This sub-test measures a student's ability to perform paper and pencil math computations.A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | After >/= 50 hours of tutoring |
| Math Fluency T Score (WJ-III) | This sub-test measures a student's ability to solve simple addition, subtraction and multiplication facts quickly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | After >/= 50 hours of tutoring |
| Spelling T Score (WJ-III) | This sub-test measures a student's ability to write orally presented words correctly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | After >/= 50 hours of tutoring |
| California Verbal Learning Test-Children's Version (CVLT-C) List A Trials 1-5 Immediate Recall T Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | After >/= 50 hours of tutoring |
| CVLT-C Trials 1-5 Semantic Clustering T Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The CVLT-C consists of five learning trials of 15 words which can be organized into three semantic categories. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | After >/= 50 hours of tutoring |
| CVLT-C Trials 1-5 Short Delay Recall T Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | After >/= 50 hours of tutoring |
| CVLT-C Trials 1-5 Long Delay Recall T Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | T scores were obtained at baseline and again at follow-up (after partcipant completed 50 hours of tutoring) |
| CVLT-C Trials 1-5 Recognition Discriminability T Score | TThe CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | After >/= 50 hours of tutoring |
| Delis Kaplan Executive Function System (D-KEFS) Number/Letter Switching T Score | The D-KEFS allows for the assessment of executive functions. There are 9 stand alone tests that can be individually or group administered. The Number-Letter Switching condition of the Trails Making sub-test specifically assesses flexibility of thinking on a visual-motor sequencing task. A participant's raw score (# of items answered correctly) is converted to a T score using tables provided in the manual. Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | After >/= 50 hours of tutoring |
Participants will receive tutoring and memory training. General Tutoring: Participants will be tutored for approximately 8-10 hours per month during the school year. Memory Training: Participants will receive memory training for approximately 8-10 hours per month during the school year. Specific memory training strategies used will include silent rehearsal training and semantic clustering training. |
| BG002 | Total | Total of all reporting groups |
| Participants |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Race (NIH/OMB) | Count of Participants | Participants |
|
| Region of Enrollment | Count of Participants | Participants |
|
| Full Scale IQ (FSIQ); Wechsler Abbreviated Scale of Intelligence (WASI) | Participants engage in 4 subtests: Block Design, Vocabulary, Similarities, and Matrix Reasoning. Participants receive a raw score on each of these 4 subtests. This raw score is converted to a T score using a score chart in the WASI manual. The T scores from all 4 subtests are summed together to obtain a Full Scale Sum of T Scores. This Full Scale Sum of T Scores is converted to a Full Scale IQ-4 Composite Score using a score chart published in the WASI manual. Higher scores indicate better intelligence. FSIQ-4 Range: 40-160. Average FSIQ-4 =100, standard deviation is +/- 15. | Mean | Standard Deviation | Scores on a scale |
|
| Verbal IQ (VIQ); Weschler Abbreviated Scale of Intelligence (WASI) | The VIQ score is comprised from the Vocabulary and Similarities subtests of the WASI-4. The raw scores from these subtests are converted to T scores using score charts in the manual. The T scores are summed together for a Verbal Sum of T Scores. This score is converted to a Composite VIQ score using a score chart in the manual. Higher scores = better Verbal IQ. Range = 45-160. Average = 100; standard deviation +/- 15. | Mean | Standard Deviation | scores on a scale |
|
| Performance IQ (PIQ); Weschler Abbreviated Scale of Intelligence (WASI) | The PIQ score is comprised from the Matrix Reasoning and Block Design subtests of the WASI-4. The raw scores from these subtests are converted to T scores using score charts in the manual. The T scores are summed together for a Performance Sum of T Scores. This score is converted to a Composite PIQ score using a score chart in the manual. Higher scores = better Performance IQ. Range = 45-160. Average = 100; standard deviation +/- 15. | Mean | Standard Deviation | scores on a scale |
|
| Letter Word Identification subtest T score of Woodcock Johnson Psycho-Educational Battery (WS-III) | This sub-test measures a student's word identification skills. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Mean | Standard Deviation | scores on a scale |
|
| Reading Fluency subtest T score of WJ-III | This sub-test measures a student's ability to read simple sentences quickly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Mean | Standard Deviation | scores on a scale |
|
| Calculations subtest T score of WJ-III | This sub-test measures a student's ability to perform paper and pencil math computations.A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Mean | Standard Deviation | scores on a scale |
|
| Math Fluency subtest T score of WJ-III | This sub-test measures a student's ability to solve simple addition, subtraction and multiplication facts quickly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Mean | Standard Deviation | scores on a scale |
|
| Spelling subtest T score of WJ-III | This sub-test measures a student's ability to write orally presented words correctly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Mean | Standard Deviation | scores on a scale |
|
| California Verbal Learning Test-Children's Version (CVLT-C) Trials 1-5 Immediate Recall T score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Mean | Standard Deviation | scores on a scale |
|
| CVLT-C Trials 1-5 Semantic Clustering T score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The CVLT-C consists of five learning trials of 15 words which can be organized into three semantic categories. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Mean | Standard Deviation | scores on a scale |
|
| CVLT-C Trials 1-5 Short Delay Recall T score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Mean | Standard Deviation | scores on a scale |
|
| CVLT-C Trials 1-5 Long Delay Recall T-Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Mean | Standard Deviation | scores on a scale |
|
| CVLT-C Trials 1-5 Recognition Discriminability T score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Mean | Standard Deviation | scores on a scale |
|
| Delis Kaplan Executive Function System (D-KEFS) Number/Letter Switching T score | The D-KEFS allows for the assessment of executive functions. There are 9 stand alone tests that can be individually or group administered. The Number-Letter Switching condition of the Trails Making sub-test specifically assesses flexibility of thinking on a visual-motor sequencing task. A participant's raw score (# of items answered correctly) is converted to a T score using tables provided in the manual. Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Mean | Standard Deviation | scores on a scale |
|
| OG001 | Tutoring + Memory Training Group | Participants will receive tutoring and memory training. General Tutoring: Participants will be tutored for approximately 8-10 hours per month during the school year. Memory Training: Participants will receive memory training for approximately 8-10 hours per month during the school year. Specific memory training strategies used will include silent rehearsal training and semantic clustering training. |
|
|
| Primary | Verbal IQ (PIQ) (WASI) | The VIQ score is comprised from the Vocabulary and Similarities subtests of the WASI-4. The raw scores from these subtests are converted to T scores using score charts in the manual. The T scores are summed together for a Verbal Sum of T Scores. This score is converted to a Composite VIQ score using a score chart in the manual. Higher scores = better Verbal IQ. Range = 45-160. Average = 100; standard deviation +/- 15. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
|
| Primary | Performance IQ (PIQ) (WASI) | The PIQ score is comprised from the Matrix Reasoning and Block Design subtests of the WASI-4. The raw scores from these subtests are converted to T scores using score charts in the manual. The T scores are summed together for a Performance Sum of T Scores. This score is converted to a Composite PIQ score using a score chart in the manual. Higher scores = better Performance IQ. Range = 45-160. Average = 100; standard deviation +/- 15. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
|
| Primary | Letter Word Identification T Score (WJ-III) | This sub-test measures a student's word identification skills. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
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|
|
| Primary | Reading Fluency T Score (WJ-III) | This sub-test measures a student's ability to read simple sentences quickly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
|
| Primary | Calculations T Score (WJ-III) | This sub-test measures a student's ability to perform paper and pencil math computations.A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
|
| Primary | Math Fluency T Score (WJ-III) | This sub-test measures a student's ability to solve simple addition, subtraction and multiplication facts quickly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
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| Primary | Spelling T Score (WJ-III) | This sub-test measures a student's ability to write orally presented words correctly. A participant's raw score (# of items answered correctly) is converted to a T score using a program (Compuscore for the WJ III, Version 2.1). Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
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| Primary | California Verbal Learning Test-Children's Version (CVLT-C) List A Trials 1-5 Immediate Recall T Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
|
| Primary | CVLT-C Trials 1-5 Semantic Clustering T Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The CVLT-C consists of five learning trials of 15 words which can be organized into three semantic categories. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
|
| Primary | CVLT-C Trials 1-5 Short Delay Recall T Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
|
| Primary | CVLT-C Trials 1-5 Long Delay Recall T Score | The CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Posted | Mean | Standard Deviation | scores on a scale | T scores were obtained at baseline and again at follow-up (after partcipant completed 50 hours of tutoring) |
|
|
|
| Primary | CVLT-C Trials 1-5 Recognition Discriminability T Score | TThe CVLT®-C measures multi-trial learning and long-term recall abilities for verbal information. The Raw scores from all trials (1-5) are summed to calculate a Total Raw Score for Trials 1-5. This Raw score is converted to a T score using the CVLT-II Comprehensive Scoring System (computer system). A higher T score indicates better performance. Range = 0-100. Average =50 with a standard deviation of =/- 10 points. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
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| Primary | Delis Kaplan Executive Function System (D-KEFS) Number/Letter Switching T Score | The D-KEFS allows for the assessment of executive functions. There are 9 stand alone tests that can be individually or group administered. The Number-Letter Switching condition of the Trails Making sub-test specifically assesses flexibility of thinking on a visual-motor sequencing task. A participant's raw score (# of items answered correctly) is converted to a T score using tables provided in the manual. Higher T scores = better performance. Range: 0-100. Average T score = 50; standard deviation =/- 10. | Posted | Mean | Standard Deviation | scores on a scale | After >/= 50 hours of tutoring |
|
|
|
| 0 |
| 8 |
| 0 |
| 8 |
| 0 |
| 8 |
| EG001 | Tutoring + Memory Training Group | Participants will receive tutoring and memory training. General Tutoring: Participants will be tutored for approximately 8-10 hours per month during the school year. Memory Training: Participants will receive memory training for approximately 8-10 hours per month during the school year. Specific memory training strategies used will include silent rehearsal training and semantic clustering training. | 0 | 10 | 0 | 10 | 0 | 10 |
Not provided
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| D006425 |
| Hemic and Lymphatic Diseases |
| D006453 | Hemoglobinopathies |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D005791 |
| Patient Care |
| D013812 | Therapeutics |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |