Buccal Versus Vaginal Misoprostol in Surgical Termination of the First Trimester Missed Abortion in Erbil

Buccal Versus Vaginal Misoprostol for Cervical Ripening Prior to Surgical Termination of the First Trimester Missed Abortion in Erbil

The purpose of this study is to determine the effectiveness of buccal misoprostol and comparing this with vaginal route of the same drug.

Inclusion Criteria:

• first trimester missed abortion

Exclusion Criteria:

• history or evidence of disorders that represent contraindication to the use of misoprostol:

  • severe pulmonary diseases
  • congenital or acquired heart diseases
  • glaucoma
  • prolonged use of corticosteroid
  • sickle cell anemia and adrenal insufficiency
  • smokers
  • known hypersensitivity to drugs
  • any evidence of infection

• patient's refusal to participate in the study

• patients with abnormal results of investigations

• patients with previous operations on cervix like conisation, cauterization, previous dilatation and curettage

• patients with complete abortion

• patients with severe bleeding that required emergency surgical evacuation of the uterus

• patients with partially dissolved tablets at the site of application in both groups