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The purpose of this study is to investigate whether cloxacillin lock is effective in prevention of double lumen infection.
Double lumen infection is one of the causes of morbidity and mortality in hemodialysis patients. Many strategies used to prevent it and one of them is antibiotic lock. Thus we select chronic hemodialysis patients and divided them into 2 groups. One group received cloxacillin and heparin as catheter lock and the second group received only heparin lock.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental | cloxacillin 100 mg/ml + heparin 1000iu/ml as catheter lock at the end of hemodialysis |
|
| 2 | Active Comparator | heparin 1000iu/ml as catheter lock at the end of hemodialysis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cloxacillin | Drug | cloxacillin 100mg/ml as catheter lock at the end of hemodialysis |
| |
| Measure | Description | Time Frame |
|---|---|---|
| catheter infection | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| maryam pakfetart, assistant professor | Shiraz nephro-urology research center | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shiraz University Hemodialysis Center | Shiraz | Fars | o98-711 | Iran |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16513483 | Background | Unver S, Atasoyu EM, Evrenkaya TR, Ardic N, Ozyurt M. Risk factors for the infections caused by temporary double-lumen hemodialysis catheters. Arch Med Res. 2006 Apr;37(3):348-52. doi: 10.1016/j.arcmed.2005.07.010. |
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| ID | Term |
|---|---|
| D003023 | Cloxacillin |
| D006493 | Heparin |
| ID | Term |
|---|---|
| D010068 | Oxacillin |
| D010406 | Penicillins |
| D047090 | beta-Lactams |
| D007769 | Lactams |
| D000577 |
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| heparin |
| Drug |
heparin 1000iu/ml as catheter lock at the end of hemodialysis |
|
| Amides |
| D009930 | Organic Chemicals |
| D013457 | Sulfur Compounds |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
| D006025 | Glycosaminoglycans |
| D011134 | Polysaccharides |
| D002241 | Carbohydrates |