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| Name | Class |
|---|---|
| ClinResearch, GmbH | OTHER |
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The purpose of this study is to describe the use of rescue medication and quality of life in adult asthmatic patients, either treated with SYMBICORT SMART® (regular dose according to physician's prescription and the current summary of product characteristics - SPC) or treated with a free combination of ICS plus LABA plus as needed SABA prescribed by the physician.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Asthma patient with specific treatment | ||
| 2 | Asthma patient on different specific treatment compared to the other group |
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| Measure | Description | Time Frame |
|---|---|---|
| Use of rescue medication | daily during 6 month |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of life | 3 times during study | |
| Efficacy variables | during 6 month | |
| Safety variables |
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Inclusion Criteria:
Confirmed diagnosis of asthma demonstrating a reversible obstruction during the last 5 years prior to visit 1.
Patients being prescribed either Symbicort SMART or a free combination of ICS and LABA with SABA as rescue inhaler and being on that treatment for at least 3 month.
A history (documented in the patient's file) of at least one severe asthma exacerbation within 24 months prior to visit 1 but not within the last 30 days prior to Visit 1.
A severe asthma exacerbation is defined as a deterioration of asthma leading to at least one of the following:
Exclusion Criteria:
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Asthma treatment will not be assigned randomly, but will be administered at the discretion of the physicians according to standard medical practice. Each site should enrol 5 patients using the Symbicort® SMART® principle and 5 patients being prescribed a free combination GCS / LABA treatment.
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| Name | Affiliation | Role |
|---|---|---|
| Kai Richter, MD | AstraZeneca | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Research Site | Aschaffenburg | Germany | ||||
| Research Site |
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| during 6 month |
| Bad Lippspringe |
| Germany |
| Research Site | Bad Sassendorf | Germany |
| Research Site | Bergkamen | Germany |
| Research Site | Berlin | Germany |
| Research Site | Bochum | Germany |
| Research Site | Bonn | Germany |
| Research Site | Braunschweig | Germany |
| Research Site | Buchholz | Germany |
| Research Site | Chemnitz | Germany |
| Research Site | Coswig | Germany |
| Research Site | Cottbus | Germany |
| Research Site | Dortmund | Germany |
| Research Site | Dresden | Germany |
| Research Site | Düsseldorf | Germany |
| Research Site | Frankfurt | Germany |
| Research Site | Fürth | Germany |
| Research Site | Gelsenkirchen | Germany |
| Research Site | Gütersloh | Germany |
| Research Site | Halle | Germany |
| Research Site | Hamburg | Germany |
| Research Site | Ketzin | Germany |
| Research Site | Köthen | Germany |
| Research Site | Leipzig | Germany |
| Research Site | Löhne | Germany |
| Research Site | Lübeck | Germany |
| Research Site | Lüdenscheid | Germany |
| Research Site | Marburg | Germany |
| Research Site | Marl | Germany |
| Research Site | Mittelbach | Germany |
| Research Site | Mühlhausen | Germany |
| Research Site | Mülheim | Germany |
| Research Site | München | Germany |
| Research Site | Oschersleben | Germany |
| Research Site | Potsdam | Germany |
| Research Site | Remscheid | Germany |
| Research Site | Saarlouis | Germany |
| Research Site | Schwetzingen | Germany |
| Research Site | Steinhagen | Germany |
| Research Site | Stockach | Germany |
| Research Site | Wedel | Germany |
| Research Site | Wesseling | Germany |
| Research Site | Weyhe | Germany |
| ID | Term |
|---|---|
| D001249 | Asthma |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
| D012130 | Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
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