The Effect of Erythropoietin at the Time of Reperfusion in Acute Myocardial Infarction

Phase 4 Study of the Effect of Human Recombinant Erythropoietin at the Time of Reperfusion in Patients With Acute Myocardial Infarction

The purpose of this study is to investigate the effect of intravenous human recombinant erythropoietin on the reperfusion injury at primary percutaneous coronary intervention in patients with acute myocardial infarction.

Inclusion Criteria:

• Acute myocardial infarction <12hr
• Age >18yrs
• First myocardial infarction
• culprit lesion : proximal to mid left anterior descending artery
• Baseline coronary flow : TIMI Grade 0~1

Exclusion Criteria:

• Patients with previous myocardial infarction
• History of thrombotic complication
• History of cerebral infarction
• Uncontrolled hypertension
• Increased hemoglobin level >17g/dL
• Patients with mechanical valve
• Cardiogenic shock