Influence of Corticoids on Renal Function in Cardiac Surgery

Influence of Corticoids on Renal Function in Cardiac Surgery

Hypothesis: Corticoid treatment in cardiac surgery works renal protective.

Study design: Randomized, double blind trial in which one group of patients will receive methylprednisolone and the other group (control) will receive placebo NaCl 0.9%.

Inclusion Criteria:

• age between 20-80 year
• patients scheduled for elective cardiac surgery.
• preoperative creatinine levels of < 2mg/dl
• no corticoid treatment

Exclusion Criteria:

• non-elective surgery
• patiënts with renal dysfunction: creatinine > 2mg/dl
• patiënts treated with corticoids