Novel Device for Reducing Catheter-Related Infections

Exploring the Use of a Novel Device for Reducing Catheter-Related Bloodstream Infections

This study is a pilot study of the safety, tolerability and efficacy of an investigational central venous catheter device used in conjunction with a standard central venous catheter. The hypothesis is that utilization of a catheter device incorporating cyanoacrylate will reduce catheter colonization by bacteria, and may decrease the rate of catheter-related bloodstream infections.

Inclusion Criteria:

• Admission in the ICU at time of catheter insertion
• Indication for central venous catheter placement
• De novo catheter insertion in the subclavian or internal jugular veins

Exclusion Criteria:

• Anticipated catheter duration < 72 hours
• Planned guidewire exchange
• Documented bacteremia within 48 hours prior to catheter placement
• Extensive skin breakdown near the site of potential catheter placement
• Emergent line placement
• Screening labs with ANC < 500 or platelets < 50K
• Hypersensitivity to cyanoacrylates or formaldehyde
• Prior enrollment in study