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MR Elastography is a new technique aimed at non-invasively measuring the stiffness of tissues. It has recently given interesting results in the assessment of liver fibrosis.
The objectives of the current study are:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pneumatic Driver | Device | Ten healthy volunteers will undergo MR Elastography using a pneumatic driver connected to a commercially available speaker and the stiffness of the left kidney will be measured. The examination will be repeated on the same volunteers at least one month later and the same stiffness measurements will be performed. |
| Measure | Description | Time Frame |
|---|---|---|
| Normal kidney stiffness (measured from MRE data) | 2 months | |
| Variability of stiffness measurement (on repeat examination) | 2 months |
| Measure | Description | Time Frame |
|---|---|---|
| Tolerance of the procedure | 2 months | |
| Percentage of partial and total technical failures | 2 months | |
| Quality criteria of stiffness measurements (area of the ROIs used for measurement, mean induced displacement measured in the ROIs) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Olivier Rouvière, MD | Hôpital E. Herriot | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Urinary an Vascular Radiology, Hôpital E. Herriot | Lyon | 69437 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 21769970 | Result | Rouviere O, Souchon R, Pagnoux G, Menager JM, Chapelon JY. Magnetic resonance elastography of the kidneys: feasibility and reproducibility in young healthy adults. J Magn Reson Imaging. 2011 Oct;34(4):880-6. doi: 10.1002/jmri.22670. Epub 2011 Jul 18. |
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| ID | Term |
|---|---|
| D005355 | Fibrosis |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| 2 months |