Physical Disability in Patients Treated With Betaferon

Physical Disability Observational Study in Patients Treated With Betaferon in Daily Practice

To gather Observation data about physical disability progression, safety and adherence during the use of Betaferon in daily practice. Patients with any type of Multiple Sclerosis (MS) (MRRS) (PSMS), under treatment with Betaferon.Open Multicentric Observational study.24 months.Evaluation of physical disability in patients treated with Betaferon, using Kurtzke's expanded disability scale (EDSS) in biannual periods

Inclusion Criteria:

• Patients with a first demyelinating event suggestive of MS, as well as patients with remittent recurrent MS (RRMS), secondary progressive MS (SPMS) and primary progressive MS (PPMS) will be able to join the study.

Exclusion Criteria:

• Pregnancy
• Patients with a history of hypersensitivity to natural or recombinant interferon-beta, human albumin or to any of the excipients
• Patients with a history of severe depressive disorders and/or suicidal ideation
• Patient with decompensated liver disease
• Patient with epilepsy not adequately controlled by treatment