Islet Function and Clinical Analyses of Transplant Recipients

Islet Function and Clinical Analyses if Transplant Recipients (Project 2 of JDFI Washington University Center For Islet Transplantation) (Please Note That the JDRFI Funded Has Ended

To follow the patterns and natural history of Islet Transplant recipients (the ones that were involved in the Modified Edmonton Protocol) using oral glucose to check sugar levels as well as insulin and C-peptide over the course of 5 years

Inclusion Criteria:

• Type 1 Diabetes with hypoglycemia unawareness that received a Islet Transplant here at Washington University
• "control" subjects were matched to the transplant recipients base upon age, height, weight, & race (and could not have diabetes)

Exclusion Criteria:

• well controlled Type 1 diabetes
• transplant failure
• unable to match potential subject to a recipient