Effect of CPAP on Blood Pressure in Patients With Sleep Apnea and Refractory Hypertension

Effect of Continuous Positive Airway Pressure (CPAP) Treatment on Blood Pressure in Patients With Sleep Apnea and Refractory Hypertension

The purpose of this study is to determine the effects of CPAP treatment on blood pressure in patients with sleep apnea syndrome (SAS) and refractory arterial hypertension (RAH).

Also, some of the mechanisms mediating SAS and RAH (systemic inflammation, oxidative stress, sympathetic hyperactivity) will be analyzed.

Inclusion Criteria:

• refractory arterial hypertension and sleep apnea with apnea-hypopnea index over 15

Exclusion Criteria:

• excessive sleepiness
• professional drivers
• secondary arterial hypertension