This program is carried out in a dedicated outpatient-clinic in the city of Hengelo for the evaluation and treatment of subjects with obesity. The program puts emphasis on intervention with appropriate diet and physical exercise, and supports the patients in achieving long-term behaviour changes. Interventions which are compared are normal vs high protein/low carb diets.

Assessment focuses on the effect of the specific diets on weight reduction after 3 months, and weight maintenance after 12 months.

Inclusion Criteria:

• Obesity with BMI > 27 kg/m2

Exclusion Criteria:

• Recent loss of body weight (>10%)
• Underlying malignancy, HIV infection, psychiatric disease
• Pregnancy or breast feeding