Olmesartan Medoxomil Versus Losartan in Patients With Hypertension

A Multi-center, Double Blind, Efficacy, and Safety Study of the Oral Angiotensin II Receptor Blocker "Olmesartan Medoxomil" Versus "Losartan" in Patients With Mild to Moderate Essential Hypertension

The purpose of this study is to determine the efficacy and safety of oral administration of olmesartan medoxomil compared to losartan in subjects with mild to moderate hypertension.

Inclusion Criteria:

• Diastolic BP 95 mm Hg - 114 mm Hg inclusive
• No participation in any clinical trial for the last 3 months

Exclusion Criteria:

• Secondary hypertension
• Malignant hypertension
• Severe arterial hypertension
• Significant cardiovascular disease
• History or clinical evidence of cerebrovascular, gastrointestinal, hematological, hepatic disease, myocardial infarction, or severe liver disorder
• Clinical evidence of renal disease, poorly controlled diabetes, known malabsorption syndromes, psychiatric/emotional problems