Effect of Platelet Rich Plasma and Keratinocyte Suspensions on Wound Healing

A New Model to Enhance Wound Healing Using Autologous Keratinocytes in Platelet Concentrates - a Prospective Randomized Trial.

This prospective randomized trial evaluated the impact of autologous keratinocytes suspended in platelet concentrates on healing skin graft donor site wounds. It was hypothesized that the treatment would speed and improve wound healing.

Inclusion Criteria:

• Skin graft donor sites total surface < 15% BSA
• Skin graft donor site size: 0.2mm deep, 30 to 40 cm2 surface area

Exclusion Criteria:

• Patients treated with immunosuppressors
• Patients treated with corticoids
• Patients suffering from terminal renal insufficiency
• Patients suffering from severe peripheral arteriopathy