The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgery

The Hemostatic and Hemodynamic Effects of Adrenaline During Endoscopic Sinus Surgery: Randomized Clinical Trial

Obtaining adequate hemostasis is crucial during endoscopic sinus surgery. Submucosal injection of local anaesthetic containing adrenaline has frequently been used to improve surgical milieu. However, injection of adrenaline has potential side effects including tachycardia, hypertension as well as inducing arrhythmia. The aim of this randomized clinical trial is to assess the hemodynamic and hemostatic effects of two different concentrations of adrenaline in local anaesthetic used during endoscopic sinus surgery.

Inclusion Criteria:

• recurrent acute sinusitis, chronic sinusitis, or nasal polyposis

Exclusion Criteria:

• bleeding disorders, under age of 18, history of cardiac disease or on antihypertensive medications