Adjunctive Mild Hypothermia Therapy to Primary Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction Complicated With Shock: A Feasibility Study

The purpose of this study is evaluate the safety and feasibility of mild therapeutic hypothermia (TH) during and 12 hours after primary percutaneous coronary intervention for acute myocardial infarction complicated with shock

Inclusion Criteria:

• Recent myocardial infarction: 24 hours of start pain
• Pump failure cardiogenic shock (defined as persistent hypotension, systolic BP < 90 mmHg, despite fluids and catecholamines infusion, with tissue hypoperfusion signs
• Candidate for immediate percutaneous reperfusion
• Maximal care support: mechanical ventilation, intraaortic balloon contrapulsation

Exclusion Criteria:

• Cardiogenic shock related to mechanical complication: free wall rupture, acute mitral regurgitation, acute VSD, tamponade
• Pregnant women
• Absence of maximal support care