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The investigators propose that clinical pharmacist interventions would reduce the rate of adverse drug events in elderly patients taking potentially inappropriate medication.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pharmacist intervention | Experimental | Patients in the intervention group will receive pharmaceutical care delivered by clinical pharmacist, which including medication review, medication reconciliation, patient education and recommended actions. |
|
| Usual care | No Intervention | Patients randomized to usual care group will receive routine review of medication by ward-based pharmacist and nurse. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pharmacist intervention | Behavioral | Medication review, medication reconciliation, and pharmacotherapy recommendation. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of unsolved drug-related problems | 14 days after randomization |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of adverse drug event during hospitalization | 14 days after randomization | |
| Number of potentially inappropriate medication | 14 days after randomization |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Liu Jen Wei, MS | Shin Kong Wo Ho-Su Memorial Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shin Kong Wo Ho-Su Memorial Hospital, Department of Pharmacy | Taipei | 111 | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 14662625 | Background | Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults: results of a US consensus panel of experts. Arch Intern Med. 2003 Dec 8-22;163(22):2716-24. doi: 10.1001/archinte.163.22.2716. | |
| 18829684 | Background | Gallagher P, O'Mahony D. STOPP (Screening Tool of Older Persons' potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers' criteria. Age Ageing. 2008 Nov;37(6):673-9. doi: 10.1093/ageing/afn197. Epub 2008 Oct 1. |
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| ID | Term |
|---|---|
| D002908 | Chronic Disease |
| D064420 | Drug-Related Side Effects and Adverse Reactions |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D064419 | Chemically-Induced Disorders |
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| 11443021 | Background | Krska J, Cromarty JA, Arris F, Jamieson D, Hansford D, Duffus PR, Downie G, Seymour DG. Pharmacist-led medication review in patients over 65: a randomized, controlled trial in primary care. Age Ageing. 2001 May;30(3):205-11. doi: 10.1093/ageing/30.3.205. |
| 17554532 | Background | Laroche ML, Charmes JP, Merle L. Potentially inappropriate medications in the elderly: a French consensus panel list. Eur J Clin Pharmacol. 2007 Aug;63(8):725-31. doi: 10.1007/s00228-007-0324-2. Epub 2007 Jun 7. |