Evaluate Safety & Efficacy of Condroflex in Subjects With OA

Phase 3 Study, to Evaluate Safety & Efficacy of the Association Condroflex + Therapeutic Exercises Compared to Placebo + Therapeutic Exercises, in Subjects With Knee OA

Primary Objective: To compare, after 12 weeks of double-blind treatment, the evolution of the improvement of pain (at rest and during / after exercise) in the questionnaire WOMAC (Western Ontario and McMaster Universities Arthritis Index), achieved with Condroflex ® oral administration(sulfate glucosamine + chondroitin sulfate sodium) in association with therapeutic exercises, compared to placebo in association with therapeutic exercises in individuals with knee OA and not exposed to prior treatment with the products under investigation.

To have osteoarthritis degree 2 or 3 / To be capable to consent

Inclusion Criteria:

• to have knee osteoarthritis degree 2 or 3
• to be capable to consent

Exclusion Criteria:

• previous drug treatment
• concomitant diseases
• concomitant drugs