A Single Dose Study to Investigate the Pharmacokinetics of MK-0941 in Participants With Renal Insufficiency (MK-0941-015-02)

A Single Dose Study to Investigate the Pharmacokinetics of MK-0941 in Subjects With Renal Insufficiency

This study will assess the pharmacokinetics of MK-0941 in participants with varying degrees of renal insufficiency.

Inclusion Criteria:

• Male or nonpregnant female age 18 to 75 years
• Female of childbearing potential on appropriate method of contraception
• Body mass index (BMI) less than or equal to 40 kg/m2
• Participant is in good health
• Participant diagnosed with Type 2 Diabetes
• Participant agrees to follow smoking restrictions
• Willing to follow the study diet restrictions

Exclusion Criteria:

• Mental or legal incapacitation
• Participant has had kidney removed
• History of Type 1 diabetes
• History of stroke, chronic seizures or major neurological disorder
• History of neoplastic disease
• Nursing mother
• Consumes greater than 4 glasses of alcoholic beverages per day
• Consumes greater than 6 servings of caffeinated beverages per day
• Participant has had surgery or donated 1 unit of blood within 1 month of screening
• Participant has history of recent eye infection within 2 weeks of study drug administration
• Clinically diagnosed with glaucoma or blindness
• Has trauma to one or both eyes