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The objective of this study is to evaluate and compare the comfort of bromfenac or nepafenac following SLT.
Open label, single armed, cross over controlled study to evaluate comfort and IOP (Intraocular Pressure) changes of specific NSAIDs post SLT. Patients (n= 25, total 50 eyes) scheduled to undergo bilateral Selective Laser Trabeculoplasty (SLT) will instill bromfenac in the first eye to undergo SLT, and the contra lateral eye will receive nepafenac.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | Xibrom (bromfenac) |
|
| 2 | Active Comparator | Nevanac (nepafenac) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Xibrom | Drug | Xibrom: two times a day for seven days in the first eye. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Tolerability of study medication | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Intraocular pressure changes | 28 days | |
| Visual Acuity | 28 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nate Kleinfeldt, M.D | Coburn-Kleinfeldt Eye Clinic | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Coburn-Kleinfeldt Eye Clinic | 3340 6 Mile Rd Livonia | Michigan | 48152 | United States |
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| Nevanac | Drug | Nevanac: three times a day for seven days in the second eye. |
|
|
| ID | Term |
|---|---|
| C053083 | bromfenac |
| C414203 | nepafenac |
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