Innate Immune Responses in Chronic Obstructive Pulmonary Disease (COPD) Patients

Innate Immune Responses in Chronic Obstructive Pulmonary Disease Patients

We hypothesize that ongoing and more severe airway inflammation in COPD may result from the impairment in activation of innate immune response

Inclusion Criteria:

• clinical diagnosis of COPD or asthma
• a ratio of prebronchodilator FEV1 to forced vital capacity (FVC) equal to or less than 0.70
• postbronchodilator FEV1 > or = 50% predicted

Exclusion Criteria:

• Exacerbation
• systemic corticosteroids
• DM, HIV and autoimmune disease
• immunosuppressive therapy