Samsung Medical Center-Lymphoma Cohort Study

Development of a Predictive Model for Treatment Outcome and Treatment-related Morbidity in a Prospective Cohort Study of Patients With Lymphoma

The purpose of this study is to establish a model which can predict the treatment outcome and the risk of treatment-related morbidity in patients with lymphoma.

Although the cure rate of lymphoma has been increased due to the development of newer effective drugs, a substantial portion of patients is still suffered from relapse. Furthermore, the treatment-related morbidity is another factor which can make the treatment outcome worse in patients with lymphoma, especially elderly patients. Thus, this study is going to assess following factors which amy probably affect the treatment outcome and the risk of treatment-related morbidity.

1. Biologic factors associated with the aggressiveness of lymphoma

   • molecular markers in serum, cytogenetic markers

2. Factors associated with the risk of treatment-related morbidity

   • comorbidity, nutrition status, performance status, quality of life at diagnosis

Inclusion Criteria:

• Patients who were diagnosed as lymphoma
• Over 15 years old
• Patients who agreed the enrollment of study
• Informed consent for sampling

Exclusion Criteria:

• Patients who do not want to join the study