Sleep Disturbances as a Risk Factor in Chronic Kidney Disease

Sleep Disturbance as a Non-Traditional Risk Factor in CKD

This study is designed to determine if either short night time sleep or poor night time sleep could be a risk factor for increasing the rate at which kidney function deteriorates in persons with mild to moderate kidney disease.

Inclusion Criteria:

• Mild to Moderate CKD
• Healthy controls age and gender matched to CKD subjects
• Regular bedtimes of at least 6h/night, sedentary lifestyle

Exclusion Criteria:

• Diabetes
• Current or previous dialysis for more than 1 month
• Uncontrolled hypertension
• Heart failure
• Liver disease
• HIV
• Hemoglobin < 10.5 g/dl
• Treatment with EProcrit, Epogen, or Aranesp
• Bone or organ transplant,
• Use of immunosuppressive drugs within past 6 months
• Current oral contraceptive use
• Current pregnancy
• Chemotherapy for malignancy within past 2 years