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Etiology of ICSCR is not known however recent studies regard the role of immunologic and infectious processes in the pathogenesis of ICSCR.one of these hypothesis is the role of helicobacter pylori in the pathogenesis of ICSCR so perhaps treatment of h pylori have positive effect on the remission of ICSCR.
we will choose 50 cases of patients with ICSCR who are infected with h.pylori.25 cases will receive anti h.pylori regiment and 25 cases as controls will receive no medication.then we will compare the time of submacular fluid resorption and macular thickness and visual acuity among these two groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Active Comparator | Oral Amoxicillin Capsule Metronidazole Tablet Omeprazole Capsule |
|
| 2 | No Intervention | No medical treatment |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| omeprazole, Amoxicillin, metronidazole | Drug | we will evaluate the effect of medication(anti h.pylori) on the remission of ICSCR |
|
| Measure | Description | Time Frame |
|---|---|---|
| Subretinal fluid level |
| Measure | Description | Time Frame |
|---|---|---|
| time of sub macular fluid absorption |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Alireza Javadzadeh | Alireza Javadzadeh | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Alireza JavadzadehTabriz | Tabriz | Iran |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40522203 | Derived | Lange CA, Qureshi R, Pauleikhoff L. Interventions for central serous chorioretinopathy: a network meta-analysis. Cochrane Database Syst Rev. 2025 Jun 16;6(6):CD011841. doi: 10.1002/14651858.CD011841.pub3. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Mar 2, 2010 | |
| Reset | Mar 26, 2010 | |
| Release | Apr 12, 2010 | |
| Reset | May 11, 2010 | |
| Release | May 21, 2010 | |
| Reset | Jun 22, 2010 | |
| Release | Oct 6, 2010 | |
| Reset | Nov 4, 2010 | |
| Release | May 22, 2011 | |
| Reset | Jun 20, 2011 | |
| Release | Jun 23, 2011 | |
| Reset | Jul 20, 2011 | |
| Release | Aug 8, 2011 | |
| Reset | Sep 8, 2011 | |
| Release | Sep 22, 2011 | |
| Reset | Oct 26, 2011 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Mar 2, 2010 | Mar 26, 2010 | |||
| Apr 12, 2010 |
| ID | Term |
|---|---|
| D056833 | Central Serous Chorioretinopathy |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D009853 | Omeprazole |
| D000658 | Amoxicillin |
| D008795 | Metronidazole |
| ID | Term |
|---|---|
| D053799 | 2-Pyridinylmethylsulfinylbenzimidazoles |
| D013454 | Sulfoxides |
| D013457 | Sulfur Compounds |
| D009930 | Organic Chemicals |
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| May 11, 2010 |
| May 21, 2010 | Jun 22, 2010 |
| Oct 6, 2010 | Nov 4, 2010 |
| May 22, 2011 | Jun 20, 2011 |
| Jun 23, 2011 | Jul 20, 2011 |
| Aug 8, 2011 | Sep 8, 2011 |
| Sep 22, 2011 | Oct 26, 2011 |
| D011725 |
| Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D001562 | Benzimidazoles |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D000667 | Ampicillin |
| D010400 | Penicillin G |
| D010406 | Penicillins |
| D047090 | beta-Lactams |
| D007769 | Lactams |
| D000577 | Amides |
| D009593 | Nitroimidazoles |
| D009574 | Nitro Compounds |
| D007093 | Imidazoles |
| D001393 | Azoles |