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This was a one-day single dose trial conducted to compare patient's preference for NasonexĀ® (mometasone) versus FlonaseĀ® nasal spray. Each patient was randomized to take one dose (2 sprays in each nostril) of Nasonex or Flonase. Thirty minutes later, each patient was to take one dose of the opposite medication. Questionnaires were given to each patient after each drug dose to evaluate patient product preference.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Nasonex Followed by Flonase | Active Comparator |
| |
| Flonase Followed by Nasonex | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mometasone Furoate Nasal Spray | Drug | One dose (2 sprays in each nostril) of Mometasone Furoate Nasal Spray |
|
| Measure | Description | Time Frame |
|---|---|---|
| Overall product preference based on subjects' answer to the question "which product do you prefer overall" | On the study day, after dose of each product |
| Measure | Description | Time Frame |
|---|---|---|
| Subject rating for likely compliance with daily dosing, | On the study day, after dose of each product | |
| Subject preference for glass or plastic bottle | On the study day, after dose of each product |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D065631 | Rhinitis, Allergic |
| ID | Term |
|---|---|
| D012220 | Rhinitis |
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
| D012130 | Respiratory Hypersensitivity |
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| ID | Term |
|---|---|
| D000068656 | Mometasone Furoate |
| D000068298 | Fluticasone |
| ID | Term |
|---|---|
| D011244 | Pregnadienediols |
| D011245 | Pregnadienes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 |
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|
| fluticasone nasal spray | Drug | One dose (2 sprays in each nostril) of fluticasone nasal spray |
|
|
| Subject response to if they would want a prescription for their preferred product and if they would recommend the product | On the study day, after dose of each product |
| Subject response to whether they preferred inhaled corticosteroid with or without aftertaste, and/or scent/odor, | On the study day, after dose of each product |
| Subject ratings for individual product attributes | On the study day, after dose of each product |
| D010038 |
| Otorhinolaryngologic Diseases |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D000730 | Androstadienes |
| D000736 | Androstenes |
| D000731 | Androstanes |