A Randomized, Double-Blind, Placebo-Controlled, Event-Driven Multicenter Study to Evaluate the Efficacy and Safety of Rivaroxaban in Subjects With a Recent Acute Coronary Syndrome
A Randomized, Double-Blind, Placebo-Controlled, Event-Driven Multicenter Study to Evaluate the Efficacy and Safety of Rivaroxaban in Subjects With a Recent Acute Coronary Syndrome
The purpose of this study is to determine whether rivaroxaban in addition to standard care reduces the risk of the composite of cardiovascular death, myocardial infarction, or stroke in patients with a recent acute coronary syndrome compared with placebo.
Acute coronary syndrome (ACS) is a serious and life threatening condition. Following an acute coronary syndrome event patients are at risk of important additional clinical events such as death, myocardial infarction, and stroke. Six months after patients present with an index event of ST-segment myocardial infarction, approximately 15% will either have died or had another episode of myocardial ischemia, and a similar situation exists for non-ST-segment elevation myocardial infarction/unstable angina patients. This randomized; double-blind; placebo controlled study will evaluate the efficacy and safety of rivaroxaban in addition to standard care in patients with a recent ACS. Patients will be given rivaroxaban (2.5 mg twice daily or 5 mg twice daily) or placebo (twice daily) in addition to standard care.
Inclusion Criteria:
Exclusion Criteria:
Coffs Harbour South, Australia
Ste-Foy, Quebec, Canada
Chile, Chile
Osorno X Región, Chile
Santiago Rm, Chile
Valdivia X Región, Chile
Beijing Prc, China
Bogotá Dc, Colombia
Cali Valle Del Cauca, Colombia
Suska 6, Croatia
Plzeò 1, Czechia
Praha 10 N/A, Czechia
Menofeya, Egypt
Bad Friedrichshall, Germany
Thessalonikis, Greece
Gandhinagar Guiarat, India
Lucknow Gpo, India
Trissur, India
Maebashi-City Gunma, Japan
Matsuyama-City Ehime, Japan
Miyazaki-Gun, Japan
Sakura-Shi, Japan
Yonago-Shi, Japan
Vilnius Lt, Lithuania
Kelantan, Malaysia
Cd. Juarez, Mexico
Hengelo Ov, Netherlands
Katowice-Ochojec, Poland
Starogard Gdanski Nap, Poland
Tg Mures, Romania
Pushkin, Saint-Petersburg, Russia
Saint-Petersbrug, Russia
Sestroretsk, Saint-Petersburg, Russia
Tumen Region, Russia
Yaroslavl Nap, Russia
Seognam-Si, Kyungki-Do, South Korea
Aviles Asturias, Spain
Phathumwan, Thailand
Khemelnitskiy, Ukraine
East Sussex, United Kingdom
Hampshire, United Kingdom