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| Name | Class |
|---|---|
| Peking Union Medical College | OTHER |
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Exposure to air pollution is an important risk factor for cardiovascular morbidity and mortality, and is associated with increased blood pressure, reduced heart rate variability, endothelial dysfunction and myocardial ischaemia. The study objectives were to assess the potential cardiovascular benefits of reducing personal particulate air pollution exposure by wearing a facemask in healthy volunteers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Visit 1 | Experimental | 2 hour city centre kerbside walk in Beijing China |
|
| Visit 2 | Experimental | 2 hour city centre kerbside walk in Beijing China |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Face mask (Dust Respirator) | Device | Subjects to wear a simple face mask for 24 hours prior to the study day and the 24 hours of the study day. They will be instructed to wear the mask as much as possible when indoors and at all times when outdoors. |
| Measure | Description | Time Frame |
|---|---|---|
| Ambulatory blood pressure | During 24 hour study period |
| Measure | Description | Time Frame |
|---|---|---|
| Heart rate | During 24 hour study period | |
| Heart rate variability | During 24 hour study period | |
| Personal air pollution exposure |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jeremy P Langrish, MB BCh MRCP | University of Edinburgh | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Medical Union College | Beijing | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24667535 | Derived | Langrish JP, Watts SJ, Hunter AJ, Shah AS, Bosson JA, Unosson J, Barath S, Lundback M, Cassee FR, Donaldson K, Sandstrom T, Blomberg A, Newby DE, Mills NL. Controlled exposures to air pollutants and risk of cardiac arrhythmia. Environ Health Perspect. 2014 Jul;122(7):747-53. doi: 10.1289/ehp.1307337. Epub 2014 Mar 25. |
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| ID | Term |
|---|---|
| D008397 | Masks |
| ID | Term |
|---|---|
| D058257 | Surgical Attire |
| D004865 | Equipment and Supplies, Hospital |
| D004864 | Equipment and Supplies |
| D011482 | Protective Devices |
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|
| No Face mask | Other | Subjects will not wear a face mask to reduce their personal exposure to air pollution |
|
| During 2 hour city centre walk |
| D000067393 | Personal Protective Equipment |
| D013523 | Surgical Equipment |
| D008420 | Manufactured Materials |
| D013676 | Technology, Industry, and Agriculture |