The purpose of this study is to compare two different in vitro fertilization (IVF) treatments: conventional IVF protocol and minimal stimulation IVF protocol, in terms of success rates, stress of treatment, drug-related side effects, multiple pregnancies and cost of treatment.

A random population of 564 sub-fertile women or couples with a female between ages of 18 and 38 years and a desire to undergo their first IVF cycle will be included in this outpatient clinical trial. The participation in this study will be approximately six months with a total of 20 to 25 visits. After successful completion of the pre-screening tests participants are randomized into one of the two arms of the study: Arm A - mini IVF protocol, and Arm B - conventional IVF protocol.

Inclusion criteria:

• Valid indication for IVF treatment
• First IVF attempt
• Female age between 18 and 38 years
• Male partner 18 years of age or older
• Both partners STD free
• Must be able to understand that they may NOT become pregnant

Exclusion criteria:

• Not willing or able to sign the consent form
• Pre-existing medical condition preventing/interfering with IVF treatment
• Abnormal IVF screening tests, which includes Complete Blood Count, Varicella titer, Rubella titer, PAP smear, Syphilis, HIV 1&2, Hepatitis B, Hepatitis C, Chlamydia, and Gonorrhea
• Abnormal pap smear
• Body Mass Index (BMI) falls below 18.5 or above 32.0
• Female participant with irregular menstrual cycles