LPL100601, A Clinical Outcomes Study of Darapladib Versus Placebo in Subjects With Chronic Coronary Heart Disease to Compare the Incidence of Major Adverse Cardiovascular Events (MACE)
LPL100601, A Clinical Outcomes Study of Darapladib Versus Placebo in Subjects With Chronic Coronary Heart Disease to Compare the Incidence of Major Adverse Cardiovascular Events (MACE)
This study will test whether darapladib can safely lower the chances of having a cardiovascular event (such as a heart attack or stroke) in people with coronary heart disease.
Subjects who qualify for the study will be randomized 1:1 to either darapladib or placebo administered in addition to standard therapy. Following the baseline visit, subjects will be expected to return for clinic visits at 1 month, 3 months, and every 6 months until the end of the study. Average time in the study for an individual subject is expected to be about 3 years.
Inclusion Criteria:
Exclusion Criteria:
CABA, Buenos Aires C1124AAJ, Argentina
Ciudad Autonoma de Buenos Aires, Buenos Aires C1405BCH, Argentina
Ciudad Autónoma de Buenos Aires, Buenos Aires C1125ABD, Argentina
Ciudad Autónoma de Buenos Aires, Buenos Aires C1437JCP, Argentina
Roeselaere, 8800, Belgium
Haerbin, 150001, China
Koebenhavn OE, 2100, Denmark
Frankfurt/M., Hesse 60594, Germany
Weyhe-Leeste, Lower Saxony 28844, Germany
Lienen-Kattenvenne, North Rhine-Westphalia 49536, Germany
Leipzg, Saxony 04109, Germany
Agia Varvara, Athens, 123 51, Greece
Magoula, Elefsina, 192 00, Greece
Voula / Athens, 166 73, Greece
Shatin, New Territories, Hong Kong
Saket,Delhi, 110017, India
Hokkaido, 063-0005, Japan
Hokkaido, 065-0033, Japan
Monterrey NL, Nuevo León 64718, Mexico
México D.F,, 07760, Mexico
Sittard-geleen, 6162 BG, Netherlands
Grafton, Auckland, 1030, New Zealand
Otahuhu, Auckland, 1640, New Zealand
Takapuna, Auckland, 0622, New Zealand
Korangi / Karachi, Pakistan
Rawalpindi Cantt, 46000, Pakistan
Ermita, Manila, 1000, Philippines
S.-Petresburg, 195067, Russia
Saint Pertersburg, 196247, Russia
St'Petersburg, 194156, Russia
Parktown West, 2193, South Africa
Seo-gu Busan, 602-739, South Korea
Seongnam-si Gyeonggi-do, 463-707, South Korea
Uijeongbu-si Kyonggi-do, 480-717, South Korea
Marid, 28040, Spain
Pozuelo de Alarcón/Madrid, 28223, Spain
San Sebastián de Los Reyes/Madrid, Spain
Santa Coloma de Gramanet (Barcelona), 08923, Spain
Valdemoro/Madrid, 28340, Spain
Hertfordshire, United Kingdom