Examination of Ocular Surface Effects With Administration of Travatan Z and XALATAN

Examination of Ocular Surface Effects With Administration of TRAVATAN Z® and XALATAN®

The purpose of this study is to compare two ophthalmic solutions in patients with open-angle glaucoma or ocular hypertension.

Inclusion Criteria:

• 18 years or older.
• Diagnosis of open-angle glaucoma or ocular hypertension in at least one eye.
• Intraocular pressure (IOP) controlled with BAK (benzalkonium chloride) preserved IOP-lowering medication for 1 year, with last 6 months on XALATAN® monotherapy.
• Best corrected visual acuity of -0.6 logMAR or better in each eye.
• Other protocol-defined inclusion criteria may apply.

Exclusion Criteria:

• Treatment with BAK preserved artificial tears within 30 days of Visit 1.
• Known or suspected Sjogren's disease.
• Uncontrolled IOP.
• History or evidence of infectious or inflammatory ocular conditions.
• Progressive retinal or optic nerve disease.
• Ocular laser surgery within 3 months of Visit 1.
• Keratorefractive ocular laser procedures, corneal surgery or surgery to the corneal surface within 1 year of Visit 1.
• Current use of punctal plugs or punctal cautery.
• Use of systemic medications that has not been stable for 30 days prior to Visit 1.
• Use of contact lens within 30 days of Visit 1.
• Other protocol-defined exclusion criteria may apply.