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To evaluate whether AN777 with or without exercise affects muscle mass change in elderly subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ad lib diet/placebo | Placebo Comparator | Ad lib diet and control product placebo |
|
| Ad lib diet/AN 777 | Experimental | Ad lib diet and AN 777 |
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| Ad lib diet/placebo/exercise | Active Comparator | Diet ad lib; exercise; and placebo |
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| Ad lib diet/ AN 777/ exercise | Experimental | Diet ad lib; AN 777; exercise |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ad lib diet and Control placebo | Other | one packet with water two times a day |
| |
| Measure | Description | Time Frame |
|---|---|---|
| The primary objective is to evaluate the effect of AN777 on muscle mass change in an elderly population while on an adequate protein intake. | 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| The secondary objective is to measure the effects of AN777 on body composition, functional outcomes, strength, and quality of life. | 24 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Catherine Johnson, PhD | Abbott Nutrition | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Health and Exercise Science, University of Oklahoma | Norman | Oklahoma | 73019 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26657810 | Derived | Fukuda DH, Stout JR, Moon JR, Smith-Ryan AE, Kendall KL, Hoffman JR. Effects of resistance training on classic and specific bioelectrical impedance vector analysis in elderly women. Exp Gerontol. 2016 Feb;74:9-12. doi: 10.1016/j.exger.2015.12.002. Epub 2015 Dec 2. | |
| 25700845 | Derived | Stout JR, Fukuda DH, Kendall KL, Smith-Ryan AE, Moon JR, Hoffman JR. beta-Hydroxy-beta-methylbutyrate (HMB) supplementation and resistance exercise significantly reduce abdominal adiposity in healthy elderly men. Exp Gerontol. 2015 Apr;64:33-4. doi: 10.1016/j.exger.2015.02.012. Epub 2015 Feb 17. |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Ad lib diet and An 777 |
| Other |
one packet with water two times a day |
|
| Ad lib diet/ placebo/ exercise | Other | one packet with water two times a day; resistance training three times a week |
|
| Ad lib diet; AN 777; exercise | Other | one packet with water two times a day; resistance training three times a week |
|