Terlipressin Administration in Septic Shock Refractory to Catecholamines

Terlipressin Administration in Septic Shock Refractory to Catecholamines Bolus vs. Continuous Drip-Phase II

terlipressin is given to refractory septic shock patients who do not respond to noradrenalin in Israel and Europe. It is given by bolus injection. we attempt to investigate weather it is better to give it by continuous drip and avoid abrupt changes in BP and heart function

Inclusion Criteria:

• septic shock patients receiving above 0.5 mcg/kg NA

Exclusion Criteria:

• allergy to terlipressin, CHF, IHD, pregnancy