Development of a New Method for Analgesia

Phase One Study and Two of a New Method for Local Analgesia

Aim: To examine a new method to perform local anesthesia in order to diminish the inconvenience by the procedure in patients before performing intubation or oesophagogastroduodenoscopy.

A phase one and two study. part one is performed as a single arm unblinded uncontrolled study in 16 obese patients undergoing awake intubation (investigational pill). The second part is a phase two study randomized single blinded study in 100 patient attending a day case endoscopy unit for oesophagogastroduodenoscopy (investigational pill versus lidocaine suspension).

Inclusion Criteria:

• Patients admitted for adipositas surgery
• Patients who attend for oesophagogastroduodenoscopy.

Exclusion Criteria:

• Severe psychiatric diseases
• Alcohol abuse