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This study will determine if rhubarb will reduced the incidence of pneumonia and improved recovery from an acute stroke. The study is designed to look at both infection rate and overall recovery and recovery of motor function, for example muscle strength and coordination.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental | rhubarb |
|
| 2 | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| rhubarb | Drug | 14 days of rhubarb |
| |
| placebo |
| Measure | Description | Time Frame |
|---|---|---|
| The lung infection rate within 14 days after stroke onset | 14 days |
| Measure | Description | Time Frame |
|---|---|---|
| Global disability on modified Rankin scale | 90 days | |
| NIH stroke scale | 90 days | |
| Barthel Index |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Integrative Medicine, Zhongshan hospital, Fudan University | Shanghai | Shanghai Municipality | 200032 | China |
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| ID | Term |
|---|---|
| D011014 | Pneumonia |
| D020521 | Stroke |
| ID | Term |
|---|---|
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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| ID | Term |
|---|---|
| C000630126 | rhubarb peony decoction |
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| Drug |
14 days of placebo |
|
| 90 days |
| Death rate | 90 days |
| Syndrome score by Traditional Chinese Medicine (TCM) standard | 90 days |
| Changes in laboratory indexes as safety assessment, including red blood cell(RBC), white blood cell(WBC), platelet(PLT), alanine transaminase (ALT), aspartate transaminase (AST), blood urea nitrogen (BUN), creatinine(Cr) in blood samples, etc. | 90 days |
| D002561 |
| Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |