Comparison of Conventional Dialysis and the Allient System

Uremic Toxin Removal, Blood Cell Kinetics, and Inflammatory Response in Patients Treated With the Allient System

The purpose of the study to determine whether the level of inflammation may be decreased, the lifespan of red blood cells increased and the clearance of waste products in the blood improved through the use of the Allient System as compared to conventional hemodialysis.

Inclusion Criteria:

• Maintenance in-center hemodialysis
• Age greater than or equal to 18 years
• Has been on hemodialysis for at least 4 months
• Uses a standard single-pass dialysis machine with a high-flux dialyzer

Exclusion Criteria:

• Hospitalization during the 8 weeks preceding enrollment
• Infection requiring antibiotic treatment during the 8 weeks preceding enrollment
• Central venous cather as dialysis access
• Uncontrollable blood coagulation anomalies
• Smokers
• Dialysis regimen other than 3 times weekly
• In ability to understand the English language and give informed consent for participation in the study