PI moved out of state.

Lasers are being used to treat Port Wine Stains (PWS), but the laser doesn't always work. Only about 10% of PWS can be completely cleared. The research team believes that the investigators can improve the response of PWS to laser therapy by using a computer program that the principal investigator of this study (Dr. Shafirstein PhD) has developed. The purpose of this study is to test the validity of this computer program. Personalized Interactive Laser Therapy (PILT) could significantly improve clinical outcomes of laser treatment of PWS.

Inclusion Criteria:

• Diagnosed with a PWS
• At least one visible PWS measuring greater than or equal to 15 mm in diameter.
• Information provided regarding alternative treatment methods, includig no treatment.
• Reading, understanding, and signing of an informed consent document.
• Children age 7 years or older has read, understood, and signed an assent document.
• Agreement to participate in the study.
• Agreement to return to at least 1 follow-up evaluation and treatment within 1 year after first treatment.
• Zubrod performance status of 0 or 1 at screening.

Exclusion Criteria:

• Inability or unwillingness of subject to participate in the study.
• Inability or unwillingness of one parent or legal guardian of the subject to sign written informed consent document.
• Subject can not return to at least 1 follow-up visit within 1 year, after the first treatment.

PI relocated and protocol was terminated, and no subject returned for treatment under protocol.