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The aim of this study was to apply the acute kidney injury criteria based on KDIGO classification in a population of patients undergoing cardiac surgery [coronary artery bypass grafting (CABG) or cardiac valve surgery (CVS)] and evaluate its impact as a predictor of 30-day mortality.
This was a single center study. We evaluated retrospectively patients from the Cardiac Surgery Intensive Care Unit in Hospital de Base, São José do Rio Preto Medical School, São Paulo, Brazil. Demographics, type of surgery, laboratory data and preoperative, perioperative, and postoperative information were retrieved from a prospectively collected database of 2878 patients older than 18 years undergoing isolated CABG (1786) or CVS (1092), from January 2003 to June 2013. After applying the exclusion criteria (51 patients with incomplete data and 23 patients with end-stage kidney disease) we analyzed 2804 patients in total, 1738 (62%) underwent CABG and 1066 (38%) underwent CVS.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| KDIGO 0 | Patients with no acute kidney injury after cardiac surgery | ||
| KDIGO 1 | Patients with acute kidney injury KDIGO stage 1 after cardiac surgery (Increase in SCr by ≥ 0.3 mg/dL (≥ 26.5 lmol/L) or 1.5 to 1.9 times baseline) | ||
| KDIGO 2 | Patients with acute kidney injury KDIGO stage 2 after cardiac surgery (2.0 to 2.9 times baseline SCr) | ||
| KDIGO 3 | Patients with acute kidney injury KDIGO stage 3 after cardiac surgery (3.0 times baseline or more; or increase in SCr to ≥ 4.0 mg/dL; or initiation of renal replacement therapy) |
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| Measure | Description | Time Frame |
|---|---|---|
| Acute Kidney Injury after cardiac surgery as a independent predictor of 30-day mortality | To test the hypothesis that the acute kidney injury based on KDIGO criteria after cardiac surgery is a independent predictor of 30-day mortality | 30 days |
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Inclusion Criteria:
patients undergoing isolated coronary artery bypass grafting or cardiac valve surgery.
Exclusion Criteria:
patients with incomplete data and patients with end-stage kidney disease.
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Patients selected consecutively after cardiac surgery (CABG or CVS) in a setting of postoperative intensive care unit.
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| Name | Affiliation | Role |
|---|---|---|
| Lilia N Maia, PhD | São José do Rio Preto Medical School | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital de Base | São José do Rio Preto | São Paulo | 15090-000 | Brazil |
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| ID | Term |
|---|---|
| D058186 | Acute Kidney Injury |
| D051437 | Renal Insufficiency |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |