Feasibility and Functionality of fPAM Imaging in Melanoma

Determine the Feasibility and Functionality of fPAM Imaging for the in Vivo Characterization and Early Diagnosis of Melanoma

Melanoma is a cutaneous malignancy that has the potential for local (skin) and regional (lymph node) recurrence. These recurrences may be difficult to detect in their earliest stages. We are attempting to use novel form of skin imaging that uses ultrasound combined with laser to identify these recurrences early, when they may be most amenable to treatment. This imaging will detect melanoma pigment below the surface of the skin and in the draining lymph nodes, as well as new blood vessel formation that occurs with these loco-regional metastases.

recruiting healthy individuals with pigmented lesions and individuals with melanoma and pigmented lesions

Inclusion Criteria:

• Adult patients (> 18 yrs of age) with recently diagnosed or a history of, Stage I - III melanoma who are able to give informed consent.

Exclusion Criteria:

• Patients with melanomas < 1mm.
• Pregnant females.
• Children and young adults < 18 yrs of age and patients who are unable to give informed consent.