Interest of the Induction With Target-controlled Inhalati... | NCT00775879

Studies
Interest of the Induction With Target-controlled Inhalation of Sevoflurane on Spikes Wave Occurrence

NCT00775879

Sponsor

University Hospital, Bordeaux

Status

Completed

Last Update Posted

Jun 18, 2026Actual

Enrollment

34Actual

Phase

Not Applicable

Conditions

General Anesthesia

Interventions

Induction with Sevoflurane

Countries

France

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

May 2013

Overall Recruitment Status or Expanded Access Status

Completed

Last Known Status

Not provided

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Mar 2006

Primary Completion Date

Jul 2008Actual

Completion Date

Jul 2008Actual

First Submitted Date

Oct 17, 2008

First Submission Date that Met QC Criteria

Oct 17, 2008

First Posted Date

Oct 20, 2008Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jun 16, 2026

Last Update Posted Date

Jun 18, 2026Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Not provided

Is FDA Regulated Device

Not provided

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Sevoflurane is widely used for induction of anaesthesia. Several studies showed EEG abnormalities during mask induction with sevoflurane. The aim of our study was to test the induction target concentration of sevoflurane on the spikes wave occurrence.

Detailed Description

Not provided

Design Module

Study Type

Interventional

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not Applicable

Interventional Study Design

Allocation

Biospecimen

No data available

No data is available for this block.

Enrollment

34Actual

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
A	Experimental	2.5% target concentration	Drug: Induction with Sevoflurane
B	Active Comparator	2.5% manually selected	Drug: Induction with Sevoflurane

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Induction with Sevoflurane	Drug		A B

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Incidence of spike wave		during anaesthesia induction with sevoflurane

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

programmed gynecological surgery
ASA 1 or 2

Exclusion Criteria:

arterial hypertension
gastro-oesophageal reflux
pregnancy
diabetes
obesity
asthma
tobacco

Accepts Healthy Volunteers

Sex

Female

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

60 Years

Standard Ages

Adult

Study Population

Not provided

Sampling Method

Not provided

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Name	Affiliation	Role
Benjamin JULLIAC, Dr	University Hospital, Bordeaux	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
CHU de Bordeaux		Bordeaux		33000	France

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
15949912	Result	Nouette-Gaulain K, Lemoine P, Cros AM, Sztark F. [Induction of anaesthesia with target-controlled inhalation of sevoflurane in adults with the ZEUS anaesthesia machine]. Ann Fr Anesth Reanim. 2005 Jul;24(7):802-6. doi: 10.1016/j.annfar.2005.04.029. French.

ID	Term
D020360	Neoadjuvant Therapy
D000077149	Sevoflurane

ID	Term
D003131	Combined Modality Therapy
D013812	Therapeutics
D008738	Methyl Ethers
D004987	Ethers